Whole Genome Bisulfite Sequencing (WGBS) Data Analysis Pipeline

Introduction DNA methylation is an important component of epigenetics and plays an important role in maintaining normal cellular function, genetic imprinting, embryonic development, and human tumorigenesis. Whole genome bisulfite sequencing (WGBS) converts unmethylated cytosine…

Tools for Sorting BAM Files

Bioinformaticsis a rapidly evolving field filled with a plethora of tools for processing and manipulating next-generation sequencing (NGS) data. The performance of¬†NGS alignment tools¬†continues to improve, but it now takes…